Urinary tract infections (UTIs) are a major public health problem worldwide. Numerous microorganisms are associated with these infections. The aim of this study was to determine the antibiotic sensitivity of different bacterial species isolated from UTIs. This prospective and cross-sectional descriptive study took place over a three months period, from 2 February to 2 May 2022. Bacterial identifications showed a predominance of Escherichia coli (52%), followed by Klebsiella pneumoniae (13%), Enteroccus spp. (9%), Enterobacter cloacae complex (8%) and Staphylococcus aureus (8%). The antibiogram showed that certain antibiotics were active on the majority of strains, including imipenem (75%), cefoxitin (65%) and ertapenem (64%), amikacin (61%). The most affected age groups by UTI were those of 51 years and over (54%), followed by those of 25 to 50 years (28%). According to Marital status, the highest prevalence of UTIs concerned Married people (78%), whereas the socio-professional characteristics showed that Housewives were the most represented (30%). The majority of infected patients came from the Commune of Ratoma (35%). An effective fight against these UTIs requiring, among other means of treatment, the identification of the germs involved in these infections and the performance of their antibiograms.
Author(s) Details:
Taliby Dos Camara
Microbiology Laboratory, Department of Biology, Faculty of Sciences, and Gamal Abdel Nasser University of Conakry BP: 1147, Republic of Guinea.
Abdoulaye Makanera
Microbiology Laboratory, Department of Biology, Faculty of Sciences, and Gamal Abdel Nasser University of Conakry BP: 1147, Republic of Guinea and Biomedical Laboratory of the China-Guinea Friendship Hospital, Kipé, Cité des Médecins, Commune Ratoma 30 BP: 710 Conakry, Republic of Guinea.
Mounaida Rachid
Microbiology Laboratory, Department of Biology, Faculty of Sciences, and Gamal Abdel Nasser University of Conakry BP: 1147, Republic of Guinea and National Reference Laboratory for Mycobacteria at the CHU Ignace Deen in Conakry, Republic of Guinea.
Mory Camara
Biomedical Laboratory of the China-Guinea Friendship Hospital, Kipé, Cité des Médecins, Commune Ratoma 30 BP: 710 Conakry, Republic of Guinea.
Recent Global Research Developments on the Public Health Impact of Urinary Tract Infections
Global Burden of UTIs: A study published in the World Journal of Urology analyzed the global, regional, and national burden of UTIs from 1990 to 2019. The study found that in 2019, over 404.6 million individuals globally had UTIs, with nearly 236,786 deaths attributed to UTIs. The age-standardized incidence rate increased significantly over the years, highlighting a rising trend in UTI burden [1] .
Long-term Trends and Disease Burden: Research published in Frontiers in Public Health examined the long-term trends and disease burden of UTIs worldwide. The study reported a 2.4 times increase in UTI-related deaths from 1990 to 2019. It also noted that the burden of UTIs varies significantly by socio-demographic status, region, sex, and age, with higher rates observed in regions with a higher socio-demographic index [2] .
Recent Developments in UTI Management: A review article in Current Urology Reports discussed recent updates in the pathology, diagnosis, management, and prevention of UTIs. The review highlighted advancements in understanding the microbial causes of UTIs, new diagnostic techniques, and emerging treatment options, including the use of probiotics and vaccines [3] .
Antibiotic Resistance in UTIs: A study in the Journal of Global Antimicrobial Resistance focused on the growing issue of antibiotic resistance in UTI pathogens. The research emphasized the need for new antimicrobial strategies and the importance of antibiotic stewardship programs to combat the rising resistance rates [2] .
Impact of UTIs on Quality of Life: Research published in BMC Public Health explored the impact of recurrent UTIs on patients’ quality of life. The study found that recurrent UTIs significantly affect physical and mental health, leading to increased healthcare utilization and economic burden.
References
- Zeng, Z., Zhan, J., Zhang, K. et al. Global, regional, and national burden of urinary tract infections from 1990 to 2019: an analysis of the global burden of disease study 2019. World J Urol 40, 755–763 (2022). https://doi.org/10.1007/s00345-021-03913-0
- Yang X, Chen H, Zheng Y, Qu S, Wang H and Yi F (2022) Disease burden and long-term trends of urinary tract infections: A worldwide report. Front. Public Health 10:888205. doi: 10.3389/fpubh.2022.888205
- Keller, L.J., Glauser, J. Urinary Tract Infection Updates and Recent Developments. Curr Emerg Hosp Med Rep 8, 41–44 (2020). https://doi.org/10.1007/s40138-020-00209-2
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