Leaf Extracts

The aim of this study was to analyze D. Oliveri using various analytical methods to screen for phytochemical components and identify bioactive substances. Qualitative, quantitative, and Gas Chromatography-Mass Spectroscopy (GC-MS) methods were used to achieve this. The identification of these compounds is useful for discovering new therapeutic potential, as well as for the development of new semi-synthetic and synthetic compounds.

The study evaluated the antiplasmodial potentials of methanol and ethanol leaf extracts of Daniellia oliveri (D. oliveri) by detecting the phytochemical components and bioactive compounds using GC-MS analysis. The leaves were collected in Anyigba, Kogi state and methanol and ethanol extracts were prepared. The results showed that alkaloid, tannin, reducing sugar, saponin, terpenoid, phenol, cardiac glycosides, and flavonoid were present in both extracts. Phenol had the highest concentration (46.14 and 43.09 mg/100g), while terpenoid had the lowest concentration (10.63 and 9.97 mg/100g) in methanol and ethanol extracts, respectively.

GC-MS analysis revealed that methanol extract contained more components than ethanol extract. Thus, the study suggests that methanol may be a better extraction solvent for GC-MS analysis of D. oliveri leaves intended for the determination of antiplasmodial activity than ethanol due to the higher number of components detected in methanol extract compared to ethanol extract. This scientific evidence could be helpful for researchers in the field of natural product discovery and development.

Author(s) Details:

Muhammed Muazu ,
Pharmacology Laboratory, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

Abdulsalami Mohammed Sani,
Department of Biotechnology, Nigerian Defence Academy, PMB 2109, Kaduna, Nigeria.

Karderam Bukar Dikwa,
Department of Biological Sciences, Nigerian Defence Academy Kaduna, Nigeria.

Deborah Madi Dibal,
Department of Biological Sciences, Nigerian Defence Academy Kaduna, Nigeria.

Kokori Bajeh Tijani,
Department of Pharmacology, Faculty of Basic Clinical Sciences, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

Junaidu Yahaya,
Department of Medical Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

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