Dentistry has evolved from simply extracting a tooth affected by caries to treating the lesion and restoring it. A new development in dental care is the early detection of caries lesions and treatment using non-surgical methods such as remineralization. The terms “early childhood caries” and “rampant caries” are sometimes used interchangeably. There are over 25 types of enzymes known as matrix metalloproteinases that can break down pericellular substrates. Total antioxidant capacity measures the amount of free radicals that a test solution can scavenge, which helps to determine the antioxidant strength of biological samples. This is essential as oxidative stress can impact the onset and progression of various inflammatory and infectious diseases, including dental caries. The aim of this review is to explore the relationship between total antioxidant capacity and matrix metalloproteinases in early childhood caries.

Author(s) Details:

Umapathy Thimmegowa,
Department of Pediatric and Preventive Dentistry, Raja Rajeswari Dental College and Hospital, No 14, Ramohalli Cross, Kumbalgodu, Mysore Road, Bengaluru-560074, India.

Soumya Pai,
Department of Pediatric and Preventive Dentistry, Raja Rajeswari Dental College and Hospital, No 14, Ramohalli Cross, Kumbalgodu, Mysore Road, Bengaluru-560074, India.

Praveen Malavalli Nagarajshetty,
Department of Orthodontics and Dentofacial Orthopaedics, KLE’ S Institute of Dental Sciences, Yeshwanthpur Suburb, Tumkur Road, Bengaluru- 560022, India.

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